Although you may have never heard of it, methylation is essential for the proper function of the human body, plays a significant role in genetics, prevents certain genetic diseases, is essential for detoxification, hormonal regulation, and more. Many people are becoming more aware of one particular methylation defect called MTHFR. There are many variants of the MTHFR defect, and very severe MTHFR defects are rare. It is estimated that up to 50 percent of the population have some form of the defect. There are ways to make sure that the body can methylate properly regardless of genetic defects.